WASHINGTON. Women often use hormone therapy to relieve hot flashes and other menopause symptoms — and new research suggests patches or creams may be safer for their blood pressure than pills.
As women’s bodies produce lower levels of reproductive hormones during menopause their risk for heart disease rises. High blood pressure further increases that risk — but it’s not clear whether there’s a link with hormone therapy for menopause symptoms.
Canadian researchers wondered if the way hormones are absorbed — orally, vaginally or through the skin — could play a role.
The University of Calgary team examined health records of more than 112,000 women ages 45 and older who filled prescriptions for at least six months’ worth of estrogen-only hormone treatment between 2008 and 2019. They tracked which women went on to develop high blood pressure at least a year after starting treatment.
While the differences weren’t huge, women who took estrogen pills had a 14% higher risk of developing hypertension compared to those using skin patches or creams, the researchers reported Monday. Oral estrogen carried a 19% greater risk than vaginal versions.
The findings were published in the journal Hypertension.
Hormone therapy has a mix of risks and benefits that mean it’s not for everyone. Today it’s prescribed not to prevent disease but to relieve menopause-related symptoms — generally using the lowest possible dose for the shortest time. Most commonly used are combination pills of estrogen and another hormone, progestin. (Estrogen-only pills typically are prescribed to women without a uterus.)
Different versions of hormone therapy may work better for different menopause symptoms, something the study didn’t address.
But it adds important clues to understanding the complex relationship between hormone therapy and blood pressure, said Dr. Garima Sharma, a women’s heart specialist with Virginia’s Inova Health System and the American Heart Association.
Sharma would like to see a more rigorous trial that compares different hormone versions. But she pointed to a possible biological explanation: Maybe oral estrogen affects enzymes linked to blood pressure as it’s being processed, while skin and vaginal versions have much more limited activity in the body.
Still, “these findings are very clinically relevant,” Sharma said in an an email, and suggest it’s especially important to monitor blood pressure in women who use oral hormone therapy.
San Pablo City, Laguna. Inilunsad na ng ang Executive Order No. 25, S. 2023 na nagtatag ng Barangay Information Office (BIO) at Officer, ayon sa ulat ng San Pablo City Hall.
Noong Biyernes ng hapon, ika-2 ng Hunyo 2023, ginanap ang opisyal na paglulunsad sa Pamana Hall sa San Pablo City Hall Compound, kung saan nilagdaan ni Mayor Vicente Belen Amante ang nasabing Executive Order noong ika-31 ng Mayo 2023.
Ang nabanggit na EO-25 ay naglalayong magtakda at magbuo ng mga Barangay Office at Officer sa 80 barangay ng lungsod.
Dumalo sa simpleng programa ng paglulunsad sina kasalukuyang Vice Mayor Justin Colago, city councilor Carmela Asaña Acebedo at Chad Pavico, Executive Assistant to the City Mayor Tintin Picazo, Seven Lakes Press Corps Secretary General Ruben Taningco, mga opisyal ng barangay information office, kinatawan mula sa Philippine Information Agency, at iba pang mga kawani at opisyal ng lokal na pamahalaan ng San Pablo.
Ang City Information Office ng San Pablo, sa pamumuno ni City Information Officer Enrico Galicia, ang nanguna sa pagbuo ng BIO sa ilalim ng patnubay ni Mayor Amante kasama ang Sangguniang Panlungsod.
Magiging tulay ng komunikasyon ang Barangay Information Office sa pagitan ng pamahalaan at mamamayan gamit ang modern communications.
Sa pamamagitan ng bagong technology, ang BIO ay naglalayong magbigay ng mabilis, epektibo, at ligtas na komunikasyon sa mga mamamayan ng barangay. Ito ay naglalayong mapadali ang paghahatid ng impormasyon, mga serbisyo, at mga programa ng pamahalaan.
Ang digital technology tulad ng online platforms, social media, at iba pang mga digital na kasangkapan ay magiging mga instrumento ng Barangay Information Office upang maabot ang mas malawak na bilang ng tao sa komunidad.
Sa pamamagitan nito, magkakaroon ng mas malaking pagkakataon ang mga mamamayan na magbigay ng kanilang mga puna, katanungan, at mga hinaing sa pamahalaan.
Layunin ng BIO na magtatag ng isang sistemang transparent at accessible para sa lahat ng mga residente ng barangay. Sa pamamagitan ng digital na teknolohiya, mas madaling maipapabatid ang mga proyekto, anunsyo, at mga programa ng pamahalaan, na magbibigay-daan sa aktibong partisipasyon at pakikilahok ng mga mamamayan sa mga lokal na isyu at patakaran.
Sa pagsasanay at paggamit ng digital na teknolohiya, inaasahang mas maayos at moderno ang serbisyo ng BIO. Ang digital na platform ay magiging daan upang maipahayag ang mga tagumpay, mga pangangailangan ng komunidad, at maging sandigan sa pagbuo ng magandang ugnayan sa pagitan ng pamahalaan at mamamayan.
Ang BIO na gagamit ng digital communication technologies ay isang malaking hakbang tungo sa mas maunlad at konektadong komunidad. Ito ay magbibigay-daan sa mas mabilis, epektibo, at inklusibong komunikasyon, na naglalayong mapabuti ang pamamalakad ng barangay at lubos na mapaglingkuran ang mga mamamayan.
Dumalo sa simpleng programa ng paglulunsad sina kasalukuyang Vice Mayor Justin Colago, city councilor Carmela Asaña Acebedo at Chad Pavico, Executive Assistant to the City Mayor Tintin Picazo, Seven Lakes Press Corps Secretary General Ruben Taningco, mga opisyal ng barangay information office, kinatawan mula sa Philippine Information Agency, at iba pang mga kawani at opisyal ng lokal na pamahalaan ng San Pablo.
Hinikayat ng mga awtoridad ang publiko na magpaturok ng COVID-19 bivalent vaccines at booster shots upang mapalakas ang resistensya laban sa sakit na ito. Ayon kay Dr. Guido David ng OCTA Research Group, bagama’t hindi ito lubos na makakaiwas sa pagkahawa ng COVID-19, makakatulong ito sa pagpigil ng malubhang impeksyon at pagpapalakas ng resistensya laban sa virus.
“Isa sa mga dahilan kung bakit nagkakaroon ng pagtaas ulit ng kaso ay dahil humihina ang ating resistensya, at nagkakaroon tayo ng waning immunity pagkatapos ng 6 na buwan mula sa pagpapabakuna o booster o pagkahawa, kaya maaari tayong maging vulnerable muli,” aniya.
“Dapat nating bigyang-pansin na nananatili ang proteksyon natin laban sa malubhang impeksyon, laban sa malalang kaso ng COVID,” dagdag ni Guido.
Ayon sa mga eksperto, mahalagang magpaturok ng COVID-19 vaccines habang ito ay libre pa, dahil malaking gastos ang pagpapagamot para sa COVID-19.
“Mas may saysay ito sa ekonomiya dahil ang bakuna ay libre pa ngayon, pero sa hinaharap, hindi na ito siguradong libre. Ngunit kung magkakasakit sila, kahit mild lang, kailangan nila ng gamot at pag-aalaga, kaya mas mapapagastos tayo,” paliwanag niya.
Noong Sabado, tumanggap ang Pilipinas ng 400,000 doses ng Pfizer bivalent COVID-19 vaccines bilang donasyon mula sa gobyerno ng Lithuania.
“Ang bivalent na bakuna ay dinisenyo upang magbigay ng proteksyon laban sa variant ng omicron,” ayon sa paliwanag ni Department of Health ASec. Leonita Gorgolon.
Pinapayuhan ng mga awtoridad ang publiko na kumuha ng tamang impormasyon tungkol sa COVID-19 vaccines at magpabakuna sa mga brand na aprubado ng mga awtoridad sa kalusugan.
Ang pagtugon sa bakuna ay mahalagang hakbang sa paglaban natin sa pandemya at pagpapanatili ng kalusugan ng ating bansa, ayon sa mga eksperto.
Tumanggap ang Pilipinas ng 400,000 doses ng Pfizer bivalent COVID-19 vaccines bilang donasyon mula sa gobyerno ng Lithuania noong Sabado.
Taking the drug osimertinib once a day after surgery reduces chance of patients dying by 51%, trials show
A pill taken once a day cuts the risk of dying from lung cancer by half, according to “thrilling” and “unprecedented” results from a decade-long global study.
Taking the drug osimertinib after surgery dramatically reduced the risk of patients dying by 51%, results presented at the world’s largest cancer conference showed.
Lung cancer is the world’s leading cause of cancer death, accounting for about 1.8 million deaths a year. The results of the late-stage study, led by Yale University, were presented at the American Society of Clinical Oncology’s (Asco) annual meeting in Chicago.
“Thirty years ago, there was nothing we could do for these patients,” said Dr Roy Herbst, the deputy director of Yale Cancer Center and lead author of the study. “Now we have this potent drug.
“Fifty per cent is a big deal in any disease, but certainly in a disease like lung cancer, which has typically been very resistant to therapies.”
The Adaura trial involved patients aged between 30 and 86 in 26 countries and looked at whether the pill could help non-small cell lung cancer patients, the most common form of the disease.
Everyone in the trial had a mutation of the EGFR gene, which is found in about a quarter of global lung cancer cases, and accounts for as many as 40% of cases in Asia. An EGFR mutation is more common in women than men, and in people who have never smoked or have been light smokers.
Speaking in Chicago, Herbst said the “thrilling” results added huge weight to earlier findings from the same trial that showed the pill also halves the risk of a recurrence of the disease.
Herbst, the assistant dean for translational research at Yale School of Medicine, said the pill was proven to be “practice-changing” and should become the “standard of care” for the quarter of lung cancer patients worldwide with the EGFR mutation.
Some patients in the UK, US and other countries are already able to access the drug, he said, but more should benefit.
Not everyone diagnosed with lung cancer is tested for the EGFR mutation, which needs to change, Herbst said, given the study’s findings. “This further reinforces the need to identify these patients with available biomarkers at the time of diagnosis and before treatment begins.”
Treatment after surgery with osimertinib, also known as Tagrisso and made by AstraZeneca, “significantly lowered” the risk of death in lung cancer patients, the trial results reported. “Adjuvant osimertinib demonstrated an unprecedented, highly statistically significant and clinically meaningful overall survival benefit in patients,” the report said.
After five years, 88% of patients who took the daily pill after the removal of their tumour were still alive, compared with 78% of patients treated with a placebo. Overall, there was a 51% lower risk of death for those who received osimertinib compared with those who received placebo.
The survival benefit “was observed consistently” in an analysis across all study subgroups, including those with stage one, stage two and stage three lung cancer. Chemotherapy had been given to 60% of those in the study, and the survival benefit of osimertinib was seen regardless of whether prior chemotherapy was received.
“It is hard to convey how important this finding is and how long it’s taken to get here,” said Dr Nathan Pennell, an Asco expert who was not involved with the study. “This shows an unequivocal, highly significant improvement in survival.”
About two-thirds of the 682 patients in the trial were women. About two-thirds of patients also had no history of smoking, which suggested the pill works for smokers and non-smokers diagnosed with lung cancer.
Angela Terry, the chair of EGFR Positive UK, a lung cancer charity, said the findings were “very exciting” and “hugely significant”.
“A five-year overall survival rate of 88% is incredibly positive news,” she said. “Having access to a drug whose efficacy is proven and whose side-effects are tolerable means patients can be confident of and able to enjoy a good quality of life for longer.”
LUCENA CITY, Quezon. Nakumpiska ang isang sling bag mula sa pag iingat ng isang mag-live-in partner na naglalaman ng hinihinalang shabu sa isinagawang anti-drug operation Sariaya Police Drug Enforcement Unit sa pamumuno ni Lt. Col. Rommel Sobredo sa Brgy. Pili, Sariaya, Quezon kamakalawa ng hapon.
Ang bag ay naglalaman ng labing-tatlong plastic sachet ng posibleng shabu na tumitimbang ng 56 gramo at nagkakahalaga ng P1,142,400.00. Natagpuan din sa loob ng bag ang P2,000 na marked money at isang cellphone.
Kinilala ni Quezon Police Provincial Office Director PCol. Ledon Monte ang mga naaresto na sina Rommel Rejano, 31 anyos, at Rose Ann Oabel, 24 anyos, pawang residente ng Purok Sta.Theresa,Barangay Dalahican, Lucena City.
Dahil sa mga ebidensyang ito, nahaharap ang mga suspek sa mga kaso ng paglabag sa Section 5 at 11 ng RA 9165 o mas kilala bilang Comprehensive Dangerous Drug Act of 2002.
Patuloy na nag iimbestiga ang mga awtoridad upang matukoy ang pinagmulan ng droga at iba pang kaugnay na impormasyon sa kaso. Hinihintay pa rin ang resulta ng pagsusuri sa mga nakumpiskang substance upang matiyak ang tunay na kalidad at kahalagahan nito.
Apple appears poised to unveil a long-rumored headset that will place its users between the virtual and real world, while also testing the technology trendsetter’s ability to popularize new-fangled devices after others failed to capture the public’s imagination.
After years of speculation, the stage is set for the widely anticipated announcement to be made Monday at Apple’s annual developers conference in a Cupertino, California, theater named after the company’s late co-founder Steve Jobs. Apple is also likely to use the event to show off its latest Mac computer, preview the next operating system for the iPhone and discuss its strategy for artificial intelligence.
But the star of the show is expected to be a pair of goggles — perhaps called “Reality Pro,” according to media leaks — that could become another milestone in Apple’s lore of releasing game-changing technology, even though the company hasn’t always been the first to try its hand at making a particular device.
Apple’s lineage of breakthroughs date back to a bow-tied Jobs peddling the first Mac in 1984 —a tradition that continued with the iPod in 2001, the iPhone in 2007, the iPad in 2010, the Apple Watch in 2014 and its AirPods in 2016.
But with a hefty price tag that could be in the $3,000 range, Apple’s new headset may also be greeted with a lukewarm reception from all but affluent technophiles.
If the new device turns out to be a niche product, it would leave Apple in the same bind as other major tech companies and startups that have tried selling headsets or glasses equipped with technology that either thrusts people into artificial worlds or projects digital images with scenery and things that are actually in front of them — a format known as “augmented reality.”
Apple’s goggles are expected be sleekly designed and capable of toggling between totally virtual or augmented options, a blend sometimes known as “mixed reality.” That flexibility also is sometimes called external reality, or XR for shorthand.
Facebook founder Mark Zuckerberg has been describing these alternate three-dimensional realities as the “metaverse.” It’s a geeky concept that he tried to push into the mainstream by changing the name of his social networking company to Meta Platforms in 2021 and then pouring billions of dollars into improving the virtual technology.
But the metaverse largely remains a digital ghost town, although Meta’s virtual reality headset, the Quest, remains the top-selling device in a category that so far has mostly appealed to video game players looking for even more immersive experiences.
Apple executives seem likely to avoid referring to the metaverse, given the skepticism that has quickly developed around that term, when they discuss the potential of the company’s new headset.
In recent years, Apple CEO Tim Cook has periodically touted augmented reality as technology’s next quantum leap, while not setting a specific timeline for when it will gain mass appeal.
“If you look back in a point in time, you know, zoom out to the future and look back, you’ll wonder how you led your life without augmented reality,” Cook, who is 62, said last September while speaking to an audience of students in Italy. “Just like today you wonder how did people like me grow up without the internet. You know, so I think it could be that profound. And it’s not going to be profound overnight.”
The response to virtual, augmented and mixed reality has been decidedly ho-hum so far. Some of the gadgets deploying the technology have even been derisively mocked, with the most notable example being Google’s internet-connected glasses released more than a decade ago.
After Google co-founder Sergey Brin initially drummed up excitement about the device by demonstrating an early model’s potential “wow factor” with a skydiving stunt staged during a San Francisco tech conference, consumers quickly became turned off to a product that allowed its users to surreptitiously take pictures and video. The backlash became so intense that people who wore the gear became known as “Glassholes,” leading Google to withdraw the product a few years after its debut.
Magic Leap, a startup that stirred excitement with previews of a mixed-reality technology that could conjure the spectacle of a whale breaching through a gymnasium floor, had so much trouble marketing its first headset to consumers in 2018 that it has since shifted its focus to industrial, healthcare and emergency uses.
Daniel Diez, Magic Leap’s chief transformation officer, said there are four major questions Apple’s goggles will have to answer: “What can people do with it? What does this thing look and feel like? Is it comfortable to wear? And how much is it going to cost?”
The anticipation that Apple’s goggles are going to sell for several thousand dollars already has dampened expectations for the product. Although he expects Apple’s goggles to boast “jaw dropping” technology, Wedbush Securities analyst Dan Ives said he expects the company to sell just 150,000 units during the device’s first year on the market — a mere speck in the company’s portfolio. By comparison, Apple sells more than 200 million iPhones, its marquee product a year. But the iPhone wasn’t an immediate sensation, with sales of fewer than 12 million units in its first full year on the market.
In a move apparently aimed at magnifying the expected price of Apple’s goggles, Zuckerberg made a point of saying last week that the next Quest headset will sell for $500, an announcement made four months before Meta Platform plans to showcase the latest device at its tech conference.
Since 2016, the average annual shipments of virtual- and augmented-reality devices have averaged 8.6 million units, according to the research firm CCS Insight. The firm expects sales to remain sluggish this year, with a sales projection of about 11 million of the devices before gradually climbing to 67 million in 2026.
But those forecasts were obviously made before it’s known whether Apple might be releasing a product that alters the landscape.
“I would never count out Apple, especially with the consumer market and especially when it comes to finding those killer applications and solutions,” Magic Leap’s Diez said. “If someone is going to crack the consumer market early, I wouldn’t be surprised it would be Apple.”
People stand outside of the Steve Jobs Theater before an event on Wednesday, Sept. 12, 2018, in Cupertino, Calif. If Apple unveils a widely anticipated headset equipped with mixed reality technology at the theater on Monday, it will be the company’s biggest new product since the introduction of the Apple Watch nearly a decade ago.(AP Photo/Marcio Jose Sanchez, File)
TALISAY, Batangas. Sinubaybayan ng Philippine Institute of Volcanology and Seismology (Phivolcs) ang pagtaas ng degassing activity ng bulkang Taal simula kahapon, Sabado ng gabi, sa pamamagitan ng nakikitang pagbuga ng volcanic fluids.
Sa isang abiso kahapon, sinabi ng Phivolcs na “ang mga fluids sa pangunahing lawa ng bulkan ay nagresulta sa malalaking pagsabog ng steam na umaabot sa 3,000 metro pataas mula sa Taal Volcano Island (TVI).
Bilang resulta nito, nakita ang volcanic smog o “vog” sa ibabaw ng caldera ng Taal, na iniulat ng mga residente ng mga bayan na nakapaligid sa lawa, kabilang ang Balete, Laurel, at Agoncillo. Inaasahang magkaroon din ng acid rain sa mga lugar kung saan makapal ang usok, na maaaring makasira sa mga pananim at makaapekto sa mga metal na bubong ng mga bahay at gusali.
Ayon sa Phivolcs, mayroon ding paglakas ng paglabas ng volcanic sulfur dioxide gas mula sa pangunahing lawa ng bulkan na naitala noong Hunyo 1, na umaabot sa 5,831 tonelada bawat araw, na mas mataas kaysa sa nakaraang buwan na mayroon lamang pangkaraniwang 3,356 tonelada bawat araw.
Paalala ng Phivolcs, dapat maging maingat ang mga komunidad na vulnerable sa epekto ng vog, lalo na ang mga nakatatanda, buntis, mga bata, at ang mga may sakit na gaya ng hika, sakit sa baga, at sakit sa puso.
Hinikayat ang mga tao sa mga apektadong lugar na manatili sa loob ng bahay at isara ang mga pinto at bintana upang pigilan ang pagpasok ng vog.
Babala ng Phivolcs na bagaman nananatiling nasa Alert Level 1 ang bulkan ng Taal, “ito ay patuloy pa rin sa hindi normal na kalagayan at hindi dapat ituring na natapos na ang pag aalburuto nito o ang panganib ng pagputok nito.
BALASORE, India. The derailment in eastern India that killed 275 people and injured hundreds was caused by an error in the electronic signaling system that led a train to wrongly change tracks and crash into a freight train, officials said Sunday.
Authorities worked to clear the mangled wreckage of the two passenger trains that derailed Friday night in Balasore district in Odisha state in one of the country’s deadliest rail disasters in decades.
An Odisha government statement revised the death toll to 275 after a top state officer put the number at over 300 on Sunday morning. The officer spoke on condition of anonymity as he was not authorized to speak to reporters.
Jaya Verma Sinha, a senior railway official, said the preliminary investigations revealed that a signal was given to the high-speed Coromandel Express to run on the main track line, but the signal later changed, and the train instead entered an adjacent loop line where it rammed into a freight loaded with iron ore.
The collision flipped Coromandel Express’s coaches onto another track, causing the incoming Yesvantpur-Howrah Express from the opposite side also to derail, she said.
The passenger trains, carrying 2,296 people, were not overspeeding, she said. Trains that carry goods are often parked on an adjacent loop line so the main line is clear for a passing train.
Verma said the root cause of the crash was related to an error in the electronic signaling system. She said a detailed investigation will reveal whether the error was human or technical.
The electronic interlocking system is a safety mechanism designed to prevent conflicting movements between trains. It also monitors the status of signals that tell drivers how close they are to a next train, how fast they can go and the presence of stationary trains on the track.
“The system is 99.9% error free. But 0.1% chances are always there for an error,” Verma said. To a question whether the crash could be a case of sabotage, she said “nothing is ruled out.”
On Sunday, a few shattered carriages, mangled and overturned, were the only remnants of the tragedy. Railway workers toiled under the sun’s glare to lay down blocks of cement to fix the broken tracks. A crew with excavators was removing mud and the debris to clear the crash site.
At one of the hospitals nearly 15 kilometers (9 miles) from the site, survivors spoke of the horror of the moment of the crash.
Pantry worker Inder Mahato could not remember the exact sequence of events, but said he heard a loud bang when the Coromandel Express crashed into the freight. The impact caused Mahato, who was in the bathroom, to briefly lose consciousness
Moments later when he opened his eyes, he saw through the door that was forced open people writhing in pain, many of them already dead. Others were frantically trying to get out from the twisted wreckage of his rail car.
For hours, Mahato, 37, remained stuck in the train’s bathroom, before rescuers scaled up the wreckage and pulled him out.
“God saved me,” he said, lying on the hospital bed while recuperating from a hairline fracture in his sternum. “I am very lucky I am alive.”
Mahato’s friends weren’t so lucky. Four of them died in the crash, he said.
Meanwhile, many desperate relatives were struggling to identify the bodies of their loved ones because of the gruesomeness of the injuries. Few others were searching hospitals to check whether their relatives were alive.
In the same hospital where Mahato was recovering from his injuries, Bulti Khatun roamed outside the premises in a dazed state, holding an identity card of her husband who was onboard the Coromandel Express and traveling to southern Chennai city.
Khatun said she visited the morgue and other hospitals to look for him, but was unable to find him.
“I am so helpless,” she said, sobbing.
Fifteen bodies were recovered on Saturday evening and efforts continued overnight with heavy cranes being used to remove an engine that settled on top of a rail car. No bodies were found in the engine and the work was completed on Sunday morning, said Sudhanshu Sarangi, director-general of fire and emergency services in Odisha.
The crash occurred at a time when Prime Minister Narendra Modi is focusing on the modernization of the British colonial-era railroad network in India, which has become the world’s most populous country with 1.42 billion people. Despite government efforts to improve safety, several hundred accidents occur every year on India’s railways, the largest train network under one management in the world.
Modi visited the crash site on Saturday and talked to rescue officials. He also visited a hospital to inquire about the injured, and spoke to some of them.
Modi told reporters he felt the pain of the crash victims. He said the government would do its utmost to help them and strictly punish anyone found responsible.
In 1995, two trains collided near New Delhi, killing 358 people in one of the worst rail accidents in India. In 2016, a passenger train slid off the tracks between the cities of Indore and Patna, killing 146 people.
Most such accidents in India are blamed on human error or outdated signaling equipment.
About 22 million people ride 14,000 trains across India every day, traveling on 64,000 kilometers (40,000 miles) of track.
___
Saaliq and Sharma reported from New Delhi.
Policemen stand guard at the site where trains that derailed, in Balasore district, in the eastern Indian state of Orissa, Sunday, June 4, 2023. Indian authorities end rescue work and begin clearing mangled wreckage of two passenger trains that derailed in eastern India, killing over 300 people and injuring hundreds in one of the country’s deadliest rail crashes in decades. (AP Photo/Rafiq Maqbool)
Pumanaw na sa edad na 55 ang beteranong aktor na si John Regala.
Kinumpirma ng pamangkin ni Regala ang kanyang pagkamatay sa social media.
“No more pain na, tito. Paalam na Tito John Regala,” sabi ni Nene Lour Billones Bendijo.
Inanunsyo rin ni entertainment columnist Aster Amoyo ang kanyang pagkamatay. Sinabi niyang namatay ang aktor ng 6:28 ng umaga matapos dumanas ng iba’t ibang sakit.
Nauna dito, naiulat na may liver cirrhosis at matinding gout si Regala.
Ipinanganak ang beteranong aktor na si John Paul Guido Boucher Scherrer noong Setyembre 12, 1967, sa mga aktor na sina Mel Francisco at Ruby Regala.
Una siyang lumabas sa “That’s Entertainment” noong dekada 1980.
Noong dekada ’90, kilala si Regala sa kanyang mga papel bilang kontrabida sa mga action films.
Napabilang siya sa mga pelikula tulad ng “Isa-Isahin Ko Kayo” (1990), “Bukas Bibitayin si Itay” (1995), at “Askal” (1997).
Noong 2011, nanalo si Regala bilang Best Supporting Actor sa Metro Manila Filmfest movie sa pelikulang “Manila Kingpin: The Asiong Salonga Story.”
Nakilahok din siya sa ilang mga serye sa telebisyon, at ang huli niyang ganap ay sa “FPJ’s Ang Probinsyano.”
Ang lamay ni Regala ay gaganapin sa St. Peter Chapels sa Tandang Sora, Quezon City. Ang detalye ng kanyang paglilibing ay hindi pa ipinapahayag.
MONTGOMERY, Ala. Alabama now has an official state cookie: The Yellowhammer Cookie.
Gov. Kay Ivey on Friday signed legislation naming the confection created by a Montgomery fourth-grader as the official state cookie.
Students at Montgomery’s Trinity Presbyterian School came up with the idea of a state cookie. Fourth-grader Mary Claire Cook submitted the winning recipe, which includes pecans, peanut butter and honey, WSFA-TV reported.
Cook brought a batch of the cookies to Ivey for the bill-signing ceremony.
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